Senadexin 30 Tablets Sennosides Laxative

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Senadexin 30 Tablets Sennosides Laxative

Regular Price: US$58.99

Special Price US$49.99

Availability: In stock

Supplier: Generic

Category: Health & Beauty Health Care

Qty:

Per tablet: Active ingredient Senadexin - 0.07 g [Sum of calcium salts of sennosides A and B from cassia (senna) leaves in terms of dry matter 20.0%] Excipients Corn starch - 0.1370 g Lactose monohydrate - 0.0340 g Talc - 0.0049 g Calcium stearate - 0.0 020 g Magnesium stearate - 0.0015 g Vanillin - 0.0003 g Methyl parahydroxybenzoate (nipagin) - 0.0003 g Pharmacological effect Laxative of plant origin. It has a laxative effect due to anthraglycosides (mainly sennosides A and B) and other glycosides. When used orally, senna glycosides pass through the stomach and small intestine unchanged without being absorbed. In the large intestine, anthraglycosides are cleaved by intestinal bacteria into pharmacologically active anthrones and anthranols, which irritate the interoreceptors of the large intestine, increase peristalsis and accelerate bowel emptying. Anthrones and anthranols prevent the absorption of water and electrolytes and promote the diffusion of water into the intestinal lumen. As a result of the osmotic effect, loosening of the feces occurs and an increase in their volume contributes to the laxative effect of anthraglycosides. The laxative effect appears after 6-10 hours. With prolonged use of the drug, the intensity of its action may decrease due to a decrease in the content of potassium in the body.