Perricone MD Acne Relief Prebiotic Acne Therapy is a simple, comprehensive system that works with your surface skin’s natural microbiome to safely, gently & effectively treat & prevent the most troublesome acne, while restoring & maintaining a healthy skin balance, for clearer, blemish-free skin. This powerful 2-step regimen is clinically proven to be non-irritating & will not strip or over-dry skin. Gentle & Soothing Cleanser (2 fl oz / 59 mL) Step 1 in your regimen. Use both day & night for fighting acne-causing bacteria. The non-foaming formula thoroughly cleanses, reduces excess oil, unclogs pores, removes dead skin cells & eliminates debris without irritating sensitive, acne-prone skin. Ultra-fine sucrose supports a healthy surface skin microbiome, yet rinses off quickly & easily, while squalane hydrates without making skin look or feel greasy. Calming Treatment & Hydrator (0.7 fl oz / 21 mL) Step 2 in your day or morning regimen after cleansing. This lightweight lotion glides onto skin to gently kill acne-causing bacteria, while nourishing with essential hydration. Lactic & succinic acids support a healthy surface skin microbiome for a clearer, more radiant complexion, while citrulline & squalane fight irritation, nourish, hydrate, soothe & visibly reduce redness. Retinol Treatment & Moisturizer (0.7 fl oz / 21 mL) Step 2 in your night regimen after cleansing. The lightweight yet nourishing formula absorbs instantly to control excess oil & helps to heal blemishes while you sleep without over-drying the skin. The powerful combination of retinol, citrulline & niacinamide helps to accelerate surface skin exfoliation & renewal, visibly calm skin & reduce redness, while gently & visibly erg imperfections overnight. Thoroughly cleanses, reduces excess oil, unclogs pores. Eliminates debris without irritating sensitive, acne-prone skin. Gently kills acne-causing bacteria. Hydrates, soothes and visibly reduces redness. Helps to heal blemishes while you sleep without over-drying the skin. DIRECTIONS Step 1: Use the Gentle & Soothing Cleanser both day and night to cleanse the face and fight acne-causing bacteria. Step 2: In the day or morning regimen after cleansing, apply the Calming Treatment & Hydrator. Step 2: In the night regimen after cleansing, apply the Retinol Treatment & Moisturizer.Number of items: 1. Item package weight: 0.65 kilograms. unit count type: count. unit count: 1.0.