PatchMD's specially designed Menopause Night Relief Patch is the best natural, all-in-one method of alleviating the challenging nighttime symptoms of menopause. May reduce headaches, sleeplessness, night sweats hot flashes, anxiety mood swings, heart palpitations and vaginal dryness. Contains Thiamin, Riboflavin, Niacinamide, Folate D3, Magnesium, Selenium, Calcium, Valerian Root Extract, Hops Flower Extract, Lemon Balm, Black Cohosh Root Extract, 5-HTP, Dong Quai Root Extract, Red Clover (please see image for amounts). Transdermal (via the skin) delivery of nutrients, is superior to oral delivery: Bypasses the stomach and liver (first pass effect), resulting in more of the nutrient compounds entering the bloodstream. Slow delivery spread over an 8 hour period is more beneficial than a large single dose. Bypassing the stomach removes potential for gut irritation. No pills to swallow! PatchMD features cutting edge 3-layer topical patch technology, designed for maximum effectiveness and durability throughout the day night. Contact Layer - this layer's exclusive, all-natural adhesive allows the patch to be worn anywhere on the body and to stay in place throughout the day night. Multi Nutrient Layer - this layer is designed to release nutrients throughout the day night. Backing Layer - this layer is uniquely designed to effectively provide structural support for the patch to be worn all day night, even with high activity. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. Made in USA. INGREDIENTS Thiamin, Riboflavin, Niacinamide, Folate D3, Magnesium, Selenium, Calcium, Valerian Root Extract, Hops Flower Extract, Lemon Balm, Black Cohosh Root Extract, 5-HTP, Dong Quai Root Extract, Red Clover DIRECTIONS Apply patch daily to an area of clean, lotion free skin, with little or no hair. Ensure skin is at full stretch if applying to mobile area. For best results, wear patches for 8 hours, there is no benefit to wearing the patch for longer. Patches can be worn during sleep (except B12 Plus). Patch is NOT waterproof. Multiple patches can be worn at the same time. SAFETY WARNING If you are pregnant, taking medication or have any other medical conditions consult a healthcare professional before using this product. See moreFree from fillers, latex, lactose, gluten and sugar. 100 natural, vegan, cruelty free not tested on animals. Superior to oral supplements - transdermal, slow release delivery, bypasses the stomach and liver, avoiding gut irritation and increg bioavailability efficacy. Convenient and durable topical patch. The best natural, all-in-one method of alleviating the challenging nighttime symptoms of menopause. No more pills to swallow! Stick on a patch instead - 30 day supply.