Panadol Extra Advance Tablets provide extra effective pain relief: Headache, toothache, backache, migraine, sore throat, period pain, helps reduce temperature, aches and pains of colds and flu, rheumatic pain, feverishness. The tablets contain two active ingredients. Paracetamol is a pain reliever and caffeine acts to further amplify the pain relieving effect of paracetamol. When you've got a headache, Panadol Extra Soluble can deliver powerful, effective relief. And it's gentle on your stomach too. When to Use Panadol Extra Soluble Panadol Extra Soluble can relieve tough head pain including Migraines. Containing paracetamol, Panadol Extra Soluble can also relieve common types of pain, including back pain, toothache, period pain and joint pain. How to Use Panadol Extra Soluble When experiencing pain, adults and children aged 16 years and over should take 2 tablets dissolved in water every 4 hours as required. Do not take more frequently than every 4 hours or more than 8 tablets in 24 hours. Children aged 12-15 years should be given 1 tablet dissolved in water every 4 hours as required. Do not take more frequently than every 4 hours or more than 4 tablets in 24 hours. Always read the label. INGREDIENTS Each tablet contains the active ingredients Paracetamol 500 mg and Caffeine 65 mg, Also includes a mixture of Sodium Methyl (E 219), Sodium Ethyl (E 215) and Sodium Propyl (E 217) Parahydroxybenzoates DIRECTIONS Please read through the information on the outside and inside of this pack before you start using this medicine. If you have any questions, or if there is anything you do not understand, ask your pharmacist. How to Take Adults and children aged 12 years and over: Swallow 2 tablets every 4 hours as needed. Do not take more frequently than every 4 hours. Do not take more than 8 tablets in 24 hours. Do not give to children under 12 years. Avoid too much caffeine in drinks like coffee and tea. High caffeine intake can cause difficulty sleeping, shaking and an uncomfortable feeling in the chest. SAFETY WARNING Take Special Care Contains paracetamol. Do not take with any other paracetamol-containing products. Ask your doctor before you take this medicine: If you have liver or kidney disease, including alcoholic liver disease. Do not exceed the stated dose. Immediate medical advice should be sought in the event of an overdose, even if you feel well, because of the risk of delayed, serious liver damage. If symptoms persist consult your doctor. Keep out of the reach and sight of children. Do not use after the exp date See morePowerful effective relief.