Take 1 capsule at the beginning of any meal that may contain gluten. NOW Gluten Digest, with BioCore DPP IV, is a comprehensive enzyme blend formulated to promote the complete digestion of cereal grains.* DPP IV (Dipeptidyl peptidase IV) is a unique enzyme with specific activity against the characteristic proline bonds found in cereal grain proteins.* Gluten Digest also includes proteases and amylases that address other protein and carbohydrate components that commonly co-occur in these foods.* BioCore DPP IV is a registered trademark of National Enzyme Company.