1 full pump dispenses about 1.3 g of cream, providing 20 mg of USP progesterone. This container yields approximately 65 pumps. Massage 1 pump into smooth skin areas such as wrists, inner arms or thighs, throat, abdomen or chest, once or twice daily. Rotate applications to these areas. Premenopausal women, use 14 days prior to the first day of menstruation, discontinue and repeat. Menopausal women, use for 21 days, discontinue for 7 days and repeat. These are general recommendations only and may need to be modified for individual needs. NOW Solutions products are not tested on animals.