20% Zinc oxide is the number one choice for parents to use on their babies when changing their diapers to prevent and treat diaper rash. Zinc Oxide instantly forms a protective barrier on the skin to seal out moisture and eliminate friction to prevent chafed skin. It also provides relief to dry cracked skin and chapped skin. Other uses of zinc oxide include treatment and prevention of minor abrasions, burns, insect bites, minor skin irritation, oozing and weeping of poison ivy, poison oak, and poison sumac. For the best result, apply a thick layer of the zinc oxide to the affected area.