What's in the Box: 3 Doses of flea and tick prevention for large dogs (21-40kg). 1-dose for 1 month effect, 3-dose supply can last for 3 months in total. Fast-acting & Long Lasting: Advanllent dog flea treatment starts working to kill fleas within 12 hours and keeps working at least 30 days. Break the Flea Life Cycle: Advanllent flea and tick treatment for dogs eliminate flea problems from the root. Truly stop and control infestations from killing adult fleas, flea eggs and larvae. No Biting Required: Different from previous flea and tick prevention for dogs, Advanllent adopts contact to achieve tick and flea control.(Including repel mosquitoes and other biting flies). It means flea and ticks die silently without biting, which prevent Lyme disease. VET Recommend Formula: Advanllent flea and tick treatment for dogs uses natural active ingredients which is safe and effective. It's a topical flea treatment for dogs, prohibited orally.