Midol Long Lasting Relief Menstrual Pain Relief Caplets with Acetaminophen offer an extended release, caffeine and aspirin-free alternative for PMS and menstrual pain relief to help you feel your best and stay active during your period. This extended-release pain reliever with acetaminophen tackles menstrual symptoms such as period cramp pain, providing headache and PMS pain relief for up to eight hours. When pain from premenstrual symptoms start, take to help ease discomfort. Available in caplet form, Midol Long Lasting Relief is easy to take and safe for adults and children 12 years and older when used as directed. Take two caplets with water every 8 hours, but do not take more than six caplets in 24 hours. Always read and follow labeled directions.