What is L-Methylfolate L-Methylfolate is a more bioavailable form of Folic Acid. By not needing to convert into 5-MTHF, this unique B supplement is able to easily support your body's needs. L-Methylfolate can be found in many forms, such as liquids, powders, pills and chewable tablets. Pure Folic Acid needs to be converted into 5-Methyltetrahydrofolate (5-MTHF) before it can be used in the body. This is where L Methyl folate comes in! How is L-Methylfolate Used L Methylfolate is an essential B vitamin most commonly used for Folate Deficiency and is known to be included in multivitamin supplements. Folate levels can easily decrease because of various factors including poor diet About Opti-Folate L-Methylfolate Now, our High Potency Activated L-Methyl folate is Non-GMO, gluten free, plus it's specially formulated to provide you with 1000 mcg per serving. If you are pregnant, nursing, taking any medications or have any medical condition, consult your doctor before use. Large quantities of L-methylfolate may mask the effects of pernicious anemia and Vitamin B-12 deficiency. If any adverse reactions occur, immediately stop using this product and consult your doctor. If seal under cap is damaged or missing, do not use. Keep out of reach of children. Store in a cool, dry place