- Full Potency
- In Foil Blister Pack
- Natural
- pH Sensitive
- Food Grade
- EnteroGuard® Coating
- S-Adenosyl Methionine
- 200 mg (Net Yield) SAM-e from 400 SAM-e tosylate Disulfate
- Highest Concentration of Active S,S Form
- Enteric-Coated Tablets
- Net Yield -400 Mg SAM-e
- Gluten Free
- Vegan
- Dietary Supplement
Promotes:
- Joint Strength
- Liver Detoxification
- Mood and Brain Function
Jarrow Formulas SAM-e 200 provides a full 200 mg SAM-e (net yield) from 400 mg of SAM-e tosylate disulfate. SAM-e 200 is manufactured under low temperature and low humidity and is enteric-coated to ensure a biologically active product.
Contains More of the Active S,S Form
Found in all living cells, SAM-e is a metabolite of methionine (an essential amino acid). SAM-e is a chiral molecule and consists of two forms: (S,S) SAM-e and (R,S) SAM-e. The biologically active form is the (S,S) structure, while the (R,S) structure is biologically inactive. Jarrow Formulas SAM-e is made naturally by microbiological fermentation and then specially processed without chemical solvents to preserve 68-80% (S,S) SAM-e, the highest active level available.
SAM-e has been clinically shown to have the following benefits:
Joint Strength
SAM-e supports the production of healthy connective tissue through transulfuration. In this process, critical components of connective tissue, known as glycosaminoglycans (GAGs), including glucosamine and chondroitin, are sulfated by SAM-E metabolites to yield sulfated GAGs, such as glucosamine sulfate and chondroitin sulfate.
Brain Metabolism
SAM-e methylation reactions are involved in the synthesis of neurotransmitters such as L-DOPA, dopamine and related hormones, serotonin, epinephrine and phosphatidylcholine (a component of lecithin).
Liver
SAM-e metabolism supports the synthesis of glutathione (GSH) and glutathione-dependent enzymes (glutathione peroxidase and glutathione-S-transferase), which are components of the body's endogenous antioxidant network and important for liver function, including phase II detoxification.
EnteroGuard is a proprietary cellulose-based, food-grade, pH-sensitive enteric coating that resist stomach acid and disintegrates in the less acidic pH of the upper intestines, where the SAMe is made available for absorption.
Other Ingredients
Cellulose, glyceryl behenate, magnesium stearate (vegetable source), silicon dioxide, mannitol, sodium starch, glycolate an enteric coating (modified cellulose, magnesium silicate, triethyl citrate, and riboflavin.
Suitable for vegetarians/vegans
No wheat, no gluten, no soybeans, no dairy, no egg, no fish/shellfish, no peanuts/tree nuts
Full Potency 400 mg SAM-e (net yield) is derived from 800 mg of SAM-e tosylate disulfate.
Warnings
Individual using prescribed medications such as antidepressants, including Selective Serotonin Re-Uptake Inhibitors (SSRI) and MAO Inhibitors should consult a physician before using. Individuals with Parkinson's disease, bi-polar disorder or manic depression should not use SAM-e. Do not use if pregnant or nursing. Do not exceed recommended intake. May cause gastrointestinal upset in some persons. If you experience discomfort, discontinue use.
Jarrow Formulas Sam-e 200 is foil blister-packed to maximize stability and safety. Do not use if outer seal of blister pack is broken.
Store in a cool, dry place.
Keep out of the reach of children.