doTERRA On Guard+ Softgels combine the proprietary blend of doTERRA On Guard Protective Blend with Black Pepper, Oregano, and Melissa essential oils for additional immune support. doTERRA On Guard+ is a great way to strengthen and maintain healthy immune function when seasonal threats are high. Encapsulated in vegetarian softgels, this distinctive blend contains essential oils known for their positive effects on the immune system and their ability to protect against environmental threats. doTERRA On Guard+ should be taken on an occasional basis. Take one or more softgels as needed to promote healthy immune function.