Doctor's Best SAM-e Double-Strength 400 mg 60 Enteric Coated Tablets

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Doctor's Best SAM-e Double-Strength 400 mg 60 Enteric Coated Tablets

Regular Price: US$99.99

Special Price US$84.99

Availability: In stock

Supplier: Doctor's Best

Category: Health & Household Vitamins & Minerals & Supplements Blended Vitamin & Mineral Supplements

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SAM-e enhance mood and neural function joint comfort and mobility liver health and detoxification


What are the benefits of SAM-e Helps enhance mood and neural function.* Helps promote joint comfort and mobility.* Helps support liver health and detoxification.*	Why take SAMe SAMe is a biological compound found in every living cell of the human body.* SAMe is limited to 3 critical metabolic pathways: trans-methylation, trans-sulfuration and amino-propylations pathways. If your body is not producing enough SAMe, you might feel blue or have trouble sleeping.*	How does it work S-Adenosyl Methionine (SAM-e) is produced by the body from ATP and the amino acid methionine which is one of the most important methyl donors in the central nervous system. Methylation (donation of methyl groups) is an essential process in ensuring the proper function of a number of organ systems. SAM-e is involved in numerous biochemical reactions in tissue including the liver, joints and brain.

Doctor's Best utilizes only the highest quality Italian Soloesse SAM-e providing slow and targeted release for improved GI tolerance and absorption. Our Double-Strength SAM-e 400 contains 400mg of active Soloesseâ SAM-e in each tablet. This ensures that you receive the most potent SAM-e product with the highest percentage of the active S,S form per serving.*

Doctor's Best SAM-e helps replenish your SAM-e levels and promote a healthy mood.* SAM-e (S-Adenosyl-L-Methionine) is naturally produced by your body and helps maintain healthy emotions. Various factors such as diet and aging can cause low levels of SAM-e, leaving you feeling unbalanced and moody.

Supplementing with SAM-e

SoloesseItalian SAM-e is processed to yield the highest available percentage of the active pure S,S form which helps mediate biochemical activity in the human body.*

SAM-e and Mood and Cognitive Function

SAM-e helps facilitate DNA enzymatic actions. These enzymatic actions are required for the healthy conversion of neurotransmitters responsible for healthy emotions, such as serotonin and dopamine. SAM-e also facilitates glutathione usage which improves the body's antioxidant defense and helps maintain acetylcholine levels necessary for cognitive function.*

SAM-e and Joint Function

In clinical trials, SAM-e has been shown to help increase joint comfort and mobility by promoting the synthesis of proteoglycans, essential components of connective tissue. *

SAM-e and Liver Function

SAM-e helps support healthy levels of glutathione, a critical antioxidant which helps protect against free radicals. SAM-e acts as a methyl donor in the synthesis and formation of phosphatidylcholine and L-cysteine, both necessary for maintaining liver health.


How does it work? S-Adenosyl Methionine (SAM-e) is produced by the body from ATP and the amino acid methionine which is one of the most important methyl donors in the central nervous system. Methylation (donation of methyl groups) is an essential process in ensuring the proper function of a number of organ systems. SAM-e is involved in numerous biochemical reactions in tissue including the liver, joints and brain.

How does it work?

S-Adenosyl Methionine (SAM-e) is produced by the body from ATP and the amino acid methionine which is one of the most important methyl donors in the central nervous system.
Methylation (donation of methyl groups) is an essential process in ensuring the proper function of a number of organ systems.
SAM-e is involved in numerous biochemical reactions in tissue including the liver, joints and brain.

Science-Based NutritionHelps Support Mood and Neural FunctionHelps Support Joint Comfort and MobilityHelps Support Liver Health and DetoxificationVeganDietary SupplementNon-GMO / Gluten Free / Soy Free / VegetarianDoctor's Best utilizes only the highest quality Italian Soloesse SAM-e providing slow and targeted release for improved GI tolerance and absorption. Our Double-Strength SAM-e 400 contains 400 mg of active Soloesse SAM-e in each tablet. This ensures that you receive the most potent SAM-e product with the highest percentage of the active S,S for per serving.

Doctor's Best SAM-e helps replenish your SAM-e levels and promote a healthy mood. SAM-e (S-Adenosyl-L-Methionine) is naturally produced by your body and helps maintain healthy emotions. Various factors such as diet and aging can cause low levels of SAM-e, leaving you feeling unbalanced and moody.

Supplementing with SAM-e

Soloesse Italian SAM-e is processed to yield the highest available percentage of the active pure S,S form which helps mediate bio-chemical activity in the human body.

SAM-e and Mood and Cognitive Function

SAM-e and Joint Function

In clinical trials, SAM-e has been shown to help increase joint comfort and mobility by promoting the synthesis of proteoglycans, essential components of connective tissue.

SAM-e and Liver Function

SAM-e helps support healthy levels of glutathione, a critical anti-oxidant which helps protect against free radicals. SAM-e acts as a methyl donor in the synthesis and formation of phosphatidylcholine and L-cysteine, both necessary for maintaining liver health.

Double Strength SAM-e is sealed in blister packs for freshness and stability.

Suggested UseAdult Use: Take 1 tablet daily between meals, or as recommended by a nutritionally-informed physician. Do not chew or crush tablet.

Other IngredientsMicrocrystalline cellulose, stearic acid, calcium chloride anhydrous, magnesium silicate, magnesium stearate, magnesium hydroxide, flake shellac dewaxed, glycerol, silica, arginine base, sodium alginate, calcium oxide.

WarningsIndividuals using antidepressant medications should consult with their prescribing physician prior to using this product. Individuals diagnosed with bipolar disease or manic depression should avoid supplementing with SAMe. Do not use if pregnant or nursing. May cause gastrointestinal discomfort in a small percentage of people.

Store product in a cool, dry place.